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- Human vs Mouse Hepatocytes in Liver ResearchThe liver is essential for protein synthesis, drug metabolism,and bile production. The rising prevalence of liver diseases has spurred substantial research on hepatic cells. In vitro studies particularly utilize primary liver hepatocytes, the epithelial cells of liver parenchyma. They constitute 60% of the liver cell population and 80% of tissue volume. As suitable in vitro models, they have...0 Commentarii 0 Distribuiri 2846 Views
- Kidney Epithelial Cells: A Crucial Tool for Nephrology Research in Drug DiscoverKidneys have an essential role to play in body homeostasis and eliminating body waste. It has been a vital focus for understanding how the drugs interact and affect them. Once they enter the bloodstream, the kidneys are responsible for clearing them out of the system. Even before we move to animal models or preclinical studies, it is necessary to test them on epithelial cells (EC). Primary...0 Commentarii 0 Distribuiri 1409 Views1
- Unveiling the Role of Mouse Lung Epithelial Cells in Health and DiseaseMouse Lung epithelial cells are crucial for respiratory function. Located at the interface between the environment and the tissue, they act as protective shields. They also participate in fluid balance, immune response, surfactant synthesis, repair processes, particulate clearance, and disease pathogenesis. Due to the changes in the structure of the lungs during the respiratory cycle, they are...0 Commentarii 0 Distribuiri 2144 Views